Cannabidiol may cause liver problems. Your healthcare provider may order blood tests to check your liver before you start taking cannabidiol and during treatment. In some cases, cannabidiol treatment may need to be stopped. Call your healthcare provider right away if you develop any of these signs and symptoms of liver problems during treatment with Cannabidiol:

• Loss of appetite, nausea, vomiting
• Fever, feeling unwell, unusual tiredness
• Yellowing of the skin or the whites of the eyes (Jaundice)
• Itching
• Unusual darkening of the urine
• Right upper stomach area pain or discomfort

Cannabidiol may cause you to feel sleepy, which may get better over time. Using certain medicines with Cannabidiol such as clobazam or alcohol may increase sleepiness. Do notdrive, operate heavy machinery, or do other dangerous activities until you know how Cannabidiol affects you. Like other antiepileptic drugs, Cannabidiol may cause suicidal thoughts or actions in a very small number of people.

Call a healthcare provider right away if you have any of these symptoms, especially if they are new, worse, or worry you:

• thoughts about suicide or dying
• attempt to commit suicide
• new or worse depression
• new or worse anxiety
• feeling agitated or restless
• panic attacks
• trouble sleeping (insomnia)
• new or worse irritability
• acting aggressive, being angry, or violent
• acting on dangerous impulses
• an extreme increase in activity and talking (mania)
• other unusual changes in behavior or mood

Pay attention to any changes, especially sudden changes in mood, behaviors, thoughts, or feelings.

Keep all follow-up visits with your healthcare provider as scheduled.

Do not take Cannabidiol if you are allergic to cannabidiol or any of the ingredients in Cannabidiol.

Before taking Cannabidiol, tell your healthcare provider about all of your medical conditions, including if you:

• have or have had depression, mood problems or suicidal thoughts or behavior.
• have liver problems.
• have abused or been dependent on prescription medicines, street drugs or alcohol.

Take Cannabidiol exactly as your healthcare provider tells you.

• Your healthcare provider will tell you how much Cannabidiol to take and when to take it.
• Measure each dose of Cannabidiol using the appropriate dosing syringes that come with Cannabidiol.

• Do not drive, operate heavy machinery, or do other dangerous activities until you know how Cannabidiol affects you. Cannabidiol may cause you to feel sleepy.

Cannabidiol can cause serious side effects, including:

• See “What is the most important information I should know about Cannabidiol?”

The most common side effects of Cannabidiol include:

• sleepiness
• decreased appetite
• diarrhea
• increase in liver enzymes
• feeling very tired and weak
• rash
• sleep problems
• fever
• vomiting
• infections

These are not all of the possible side effects of Cannabidiol. For more information, ask your healthcare provider .

Tell your healthcare provider about any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects

Store Cannabidiol at temperature mentioned on bottle pack.

• Always store Cannabidiol in an upright position.
• Do not freeze.
• Keep the cap tightly closed.
• Use Cannabidiol within 12 weeks of first opening the bottle. Throw away (dispose of) any unused medicine after 12 weeks.

Keep Cannabidiol out of the reach of children

General Information.

 Do not use Cannabidiol for a condition for which it was not prescribed. Do not give Cannabidiol to other people, even if they have the same symptoms that you have. It may harm them.

You can ask your pharmacist or healthcare provider for information about Cannabidiol that is written for health professionals.